| Joe Allen |
Two shuttle missions (STS-5, STS-51A) |
| Dan Brandenstein |
Four shuttle missions (STS-8, STS-51G, STS-32, STS-49) |
| Dick Covey |
Four shuttle missions (STS-51I, STS-26, STS-38, STS-61), including the first Hubble Space Telescope servicing mission (STS-61) |
| Bob Crippen |
Four shuttle missions (STS-1, STS-7, STS-41C, STS-41G), including the maiden voyage of the Space Shuttle Columbia, and former director of the Kennedy Space Center |
John Fabian  |
Two shuttle missions (STS-7, STS-51G) |
| Owen Garriott |
Spent 56 days in space on Skylab 3 and flew on the ninth Space Shuttle mission (STS-9) |
| John Glenn |
First American to orbit, flew aboard Space Shuttle Discovery on STS-95, retired U.S. Senator from Ohio |
Ronald Grabe  |
Four shuttle missions (STS-51J, STS-30, STS-42, STS-57) |
| Rick Hauck |
Three shuttle missions (STS-7, STS-51A, STS-26), including commanding the first post-Challenger flight (STS-26) |
| Thomas D. Jones |
Four shuttle missions (STS-59, STS-68, STS-80, STS-98) |
Jon McBride  |
One shuttle mission (STS-41G) |
Mike McCulley  |
One shuttle mission (STS-34) |
Mike Mullane  |
Three shuttle missions (STS-41D, STS-27, STS-36) |
George (Pinky) Nelson  |
Three shuttle missions (STS-41C, STS-61C, STS-26) |
Rick Searfoss  |
Three shuttle missions (STS-58, STS-76, STS-90) |
Bob Springer  |
Two shuttle missions (STS-29, STS-38) |
| Paul Weitz |
Spent 28 days in space on Skylab 2 and flew on the sixth Space Shuttle mission (STS-6) |
| John Young |
Flew on Gemini 3, commanded Gemini 10, orbited the Moon on Apollo 10, walked on the Moon as Apollo 16 Commander, commanded the first Space Shuttle mission STS-1 and the 9th shuttle flight, STS-9. Young was the first person to fly in space six times. |